The P365 FUSE brings the ergonomics and performance of the P365 platform in a full-sized frame. The pistol features a 4.3-inch carbon steel barrel with a durable DLC finish along with Sig Sauer's polymer LXG grip module that sports a laser-engraved grip texture, 1913 accessory rail, and removable flared magwell. The slide features a fiber-optic front sight and serrated rear sight combo and comes with an optics ready cut designed for RMSc optics.

This model includes two 17-round magazines and one 21-round magazine.